Results
| PMID | 25134292 |
| Gene Name | KLK3 |
| Condition | Endometriosis |
| Association |
Associated |
| Sex | Female |
|
Clin Exp Obstet Gynecol. 2014;41(4):432-5. Evsen, M S| Sak, M E| Soydinc, H E| Guven, S| Basaranoglu, S| Hatipoglu, N K| Evliyaoglu, O| Gul, T OBJECTIVE: The aim of the present study was to evaluate the levels of serum androgens and prostate-specific antigen (PSA) levels in patients with endometriosis. MATERIALS AND METHODS: Patients with Stage III/IV (advanced stage) endometriosis were compared to controls with respect to basal serum levels of total testosterone (T), free testosterone (fT), androstenedion (A), dehydroepiandrosterone (DHEA), dehydroepiandrosterone-sulphate (DHEA-S), and PSA in the early follicular phase of menstrual cycle for this prospective case control study. RESULTS: Level of T, fT, A, DHEA, and DHEA-S were higher in patients with endometriosis when compared to control subjects, but the difference was not statistically significant. The mean PSA level was 0.0074 +/- 0.0120 ng/ml in patients with endometriosis and 0.0059 +/- 0.0056 ng/ml in control group and there was no statistically significant difference between groups (p = 0.58). CONCLUSION: Serum basal androgens and PSA levels are higher in endometriosis group with respect to control but the differences are not statistically significant. Mesh Terms: Adult| Androstenedione/*blood| Case-Control Studies| Dehydroepiandrosterone/*blood| Endometriosis/*blood/physiopathology| Female| Follicular Phase/physiology| Humans| Prospective Studies| Prostate-Specific Antigen/*blood| Testosterone/*blood| Y |
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